Simulation in thromboelastography: Platelet mapping assay (Part - I)

Thromboelastography-platelet mapping expanding in non-cardiac surgery.

We read the work of Preisman et al. investigating the preoperative use of point-of-care-modified thromboelastography-platelet mapping (TEG-PM) in patients scheduled for surgical coronary revascularization [1] with great interest. We have been using TEG-PM for preoperative testing of patients with coronary stents or status post coronary artery bypass grafting (CABG) also receiving clopidogrel an...

Incidence of Platelet Dysfunction by Thromboelastography–Platelet Mapping in Children Supported with ECMO: A Pilot Retrospective Study

BACKGROUND Bleeding complications are common and decrease the odds of survival in children supported with extracorporeal membrane oxygenation (ECMO). The role of platelet dysfunction on ECMO-induced coagulopathy and resultant bleeding complications is not well understood. The primary objective of this pilot study was to determine the incidence and magnitude of platelet dysfunction according to ...

Evaluation of the TEG® platelet mapping™ assay in blood donors

BACKGROUND Monitoring of antiplatelet therapy in patients at cardiovascular risk is difficult because existing platelet function tests are too sophisticated for clinical routine. The whole blood TEG Platelet Mapping assay measures clot strength as maximal amplitude (MA) and enables for quantification of platelet function, including the contribution of the adenosine diphosphate (ADP) and thrombo...

Platelet mapping assay interference due to platelet activation in heparinized samples.

OBJECTIVES Thromboelastography Platelet Mapping (TEGPM) is an assay designed to detect platelet inhibition due to aspirin or clopidogrel-like drugs. The purpose of this study was to evaluate potential causes of error in the design or operation of the assay. METHODS We evaluated percent inhibition of platelets due to aspirin or clopidogrel using TEGPM, which measures clot viscoelastic maximum ...

Sound Field Simulation by Computational Acoustics - Part I: Simulation Algorithm